Threats of Concomitant Use or Discontinuation of Cytochrome P450 2D6 Inhibitors The concomitant utilization of tramadol hydrochloride tablets with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) may possibly lead to a rise in tramadol plasma stages along with a reduce during the levels of the Lively metabolite, M1.Tramadol debe ser